Kombiglyze XR 5mg/1000mg Tablet

Manufacturer AstraZeneca
Composition Saxagliptin (5mg), Metformin (1000mg)
Type Tablet
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How to use Kombiglyze XR 5mg/1000mg Tablet

Take this medication in the dose and also duration as encouraged by your medical professional. Swallow it in its entirety. Do not chew, squash or break it. Kombiglyze XR 5mg/1000mg Tablet is to be taken with food. Kombiglyze XR 5mg/1000mg Tablet might cause stomach upset if taken on empty stomach.


How Kombiglyze XR 5mg/1000mg Tablet works in the body

According to scientific research, this medicine works in the body per below(ME/1)

This medication is a mix of 2 antidiabetic medications: Saxagliptin as well as Metformin. Saxagliptin is a dipeptidyl peptidase-4 prevention which functions by raising the launch of insulin from pancreatic as well as reducing the hormonal agents that increase blood glucose degrees. This lowers both fasting as well as postmeal sugar degrees. Metformin is an anti-diabetic drug (biguanide). It functions by reducing sugar manufacturing in the liver, postponing sugar absorption from intestinal tracts as well as raising the body’s level of sensitivity to insulin.


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What are the Side effects of Kombiglyze XR 5mg/1000mg Tablet

Scientific studies indicate, below mentioned side effects may occur while taking this medicine such as(ME/2)

  • Diarrhea
  • Nausea
  • Vomiting
  • Stomach upset
  • Headache
  • Nasal congestion
  • Sore throat
  • Respiratory tract infection
  • Hypoglycaemia (low blood sugar level) in combination with insulin or sulphonylurea

Precautions to be taken while taking Kombiglyze XR 5mg/1000mg Tablet

As per several scientific studies, some precautions need to be taken while taking this medicine such as(ME/3)

  1. Take it with food to decrease your possibility of having an indigestion.
  2. Possibilities of weight gain and also reduced blood sugar level are minimal as contrasted to various other diabetics issues medications.
  3. Educate your medical professional concerning your diabetic issues therapy if you are because of have surgical treatment under a basic anaesthetic.
  4. Inform your physician quickly if you experience any kind of deep or fast breathing, relentless nausea or vomiting, throwing up, and also belly discomfort as this medication might trigger an unusual yet significant problem called lactic acidosis, which is an unwanted of lactic acid in the blood.

Safety instructions before taking Kombiglyze XR 5mg/1000mg Tablet

  • Alcohol : Caution required : It is not safe to drink alcohol with this medicine. Taking this medicine with alcohol can cause lactic acidosis and you may experience malaise, respiratory distress, slow or irregular heartbeat, sleepiness, stomach upset, or other unusual symptoms.
  • Pregnancy : Possibly secure: This medicine is possibly secure to make use of during pregnancy. Pet researches have actually shown low or no adverse result on the unborn child, nevertheless, there are limited human researches. Please get in touch with medical professional before eating this medication.
  • Lactation : Most likely secure: This medication is possibly safe to utilize during lactation. Minimal human information suggests that the drug does not stand for a significant danger to the infant.
  • Kidney : Care called for: This medication must be utilized with caution in clients with kidney disease. Dose adjustment of This medication may be needed. Please speak with medical professional prior to consuming this medicine.Use of this medicine is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function test is advisable while you are taking this medicine.
  • Liver : Care needed: This medication needs to be utilized with care in individuals with liver disease. Dosage modification of this medicine might be required. Please seek advice from physician prior to eating this medication This medicine is generally started with low dose in patients with mild to moderate liver disease and its use is not recommended in patients with severe liver disease.
  • Driving : Care called for: Your ability to drive may be impacted if your blood sugar level is reduced or high. If this occurs, do not drive.

Frequently asked questions

Q: What should i do if i forgot to take Kombiglyze XR 5mg/1000mg Tablet

A: Take it as soon as possible.


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